RET, Mouse, Clone: 8D10C9, Abnova™

Catalog No.	Quantity
89-108-548	100 μL

Catalog No. 89-108-548 Supplier Abnova Corporation Supplier No. MAB10361

Description

Mouse monoclonal antibody raised against partial recombinant RET.

This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. [provided by RefSeq

Specifications

• Antigen: RET
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: 8D10C9
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against partial recombinant RET.
• Dilution: ELISA (1:10000) Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user.
• Formulation: In ascites (0.03% sodium azide)
• Gene: RET
• Gene Alias: CDHF12/HSCR1/MEN2A/MEN2B/MTC1/PTC/RET-ELE1/RET51
• Gene Symbols: RET
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to amino acids 896-1063 of human RET.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5979
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1