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Description
This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq
Specifications
Specifications
| Antigen | RGS17 |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Clone | 2H4 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a full-length recombinant RGS17. |
| Formulation | ascites with no preservative |
| Gene | RGS17 |
| Gene Accession No. | BC013117 |
| Gene Alias | RGS-17/RGSZ2/hRGS17 |
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