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Description
The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq
Specifications
Specifications
| Antigen | RIPK3 |
| Applications | Western Blot |
| Classification | Monoclonal |
| Clone | Rippy-3 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against recombinant RIPK3. |
| Dilution | The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (0.02% sodium azide) |
| Gene | RIPK3 |
| Gene Alias | RIP3 |
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