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Perlecan Mouse anti-Human, Unlabeled, Clone: 5D7-2E4, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 565781

Catalog No. BDB565781


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Description

Description

The 5D7-2E4 monoclonal antibody specifically recognizes the protein core of Perlecan (PRCAN), which has a calculated molecular mass of ∽460 kDa. Smaller molecular mass species of Perlecan have also been described. Perlecan is also known as Heparan sulfate proteoglycan 2 (HSPG2), or Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG). Perlecan is a large multidomain proteoglycan that is produced by epithelial and endothelial cells. It is a major component of the vascular extracellular matrix and helps sustain endothelial barrier function. Perlecan inhibits smooth muscle cell proliferation and serves as an attachment substrate for cells. It plays essential roles in normal cartilage, heart and vascular development, as well as, in the response to vascular injury.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

Perlecan
Monoclonal
0.5mg/mL
PRCAN; HSPG2; HSPG; Endorepellin; LG3; PLC; SJA; SJS; SJS1
Mouse
Affinity Purified
RUO
Human
IgG1 κ
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen), Western Blot
5D7-2E4
Unconjugated
Aqueous buffered solution containing ≤0.09% sodium azide.
Purified full-length Human Perlecan
50 μg
Primary
Store undiluted at 4°C
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