Mouse anti-S100A1, Clone: 4C4.9 + S100A1/1012, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP2445930.2MG

Catalog No. NBP24459302

Description

Ensure accurate, reproducible results in Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Specifications

• Antigen: S100A1
• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Dilution: Western Blot 0.5 - 1.0 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.25 - 0.5 ug/ml, Immunofluorescence 1 - 2 ug/ml
• Gene Accession No.: P23297
• Gene Symbols: S100A1
• Immunogen: Purified bovine brain S100 protein (4C4.9); Recombinant full-length human S100A1 protein (S100A1/1012)
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: S100 belongs to the family of calcium binding proteins. S100A and S100B proteins are two members of the S100 family. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. S-100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lipocytes, skeletal and cardiac muscle, Schwann cells, epithelial and myoepithelial cells of the breast, salivary and sweat glands, as well as in glial cells. Neoplasms derived from these cells also express S-100 protein, albeit non-uniformly. A large number of well-differentiated tumors of the salivary gland, adipose and cartilaginous tissue, and Schwann cell-derived tumors express S-100 protein. Almost all malignant melanomas and cases of histiocytosis X are positive for S-100 protein. Despite the fact that S-100 protein is an ubiquitous substance, its demonstration is of great value in the identification of several neoplasms, particularly melanomas and their metastases.
• Content And Storage: Store at 4C.
• Isotype: IgG

• Applications: Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
• Clone: 4C4.9 + S100A1/1012
• Conjugate: Unconjugated
• Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
• Gene Alias: protein S100-A1, S100 alpha, S100 calcium binding protein A1, S100 calcium-binding protein A1S100, S-100 protein alpha chain, S-100 protein subunit alpha, S100 protein, alpha polypeptide, S100A, S100-alpha
• Host Species: Mouse
• Molecular Weight of Antigen: 11 kDa
• Quantity: 0.2 mg
• Research Discipline: Astrocyte Markers, Breast Cancer, Cancer, Cell Biology, Cellular Markers, Cytoskeleton Markers, Hypoxia, Lipid and Metabolism, Neuronal Cell Markers, Neuroscience, Peroxisome Markers, Signal Transduction
• Gene ID (Entrez): 6271
• Target Species: Human, Mouse, Rat, Primate
• Form: Purified

For Research Use Only