SCD, Mouse, Clone: CD.E10, Abnova™

Mouse monoclonal antibody raised against full-length recombinant SCD.

Supplier:  Abnova Corporation MAB5546

Catalog No. 89-112-292

Description

Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an iron-containing enzyme that catalyzes a rate-limiting step in the synthesis of unsaturated fatty acids. The principal product of SCD is oleic acid, which is formed by desaturation of stearic acid. The ratio of stearic acid to oleic acid has been implicated in the regulation of cell growth and differentiation through effects on cell membrane fluidity and signal transduction. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 and SCD5 (MIM 608370), have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates (Zhang et al. (1999) [PubMed 10229681]; Wang et al., 2005 [PubMed 15907797]).[supplied by OMIM

Specifications

• Antigen: SCD
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: The optimal working dilution should be determined by the end user.
• Gene: SCD
• Gene Symbols: SCD
• Immunogen: Recombinant protein corresponding to full length human SCD.
• Regulatory Status: RUO
• Gene ID (Entrez): 6319
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG2b

• Applications: ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
• Clone: CD.E10
• Description: Mouse monoclonal antibody raised against full length recombinant SCD.
• Formulation: In PBS, pH 7.4 (0.05% sodium azide)
• Gene Alias: FADS5/MSTP008/SCD1
• Host Species: Mouse
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Form: Liquid