SELE, Mouse, Clone: 1.2B6, Abnova™

Catalog No.	Quantity
89-112-747	100 μg

Catalog No. 89-112-747 Supplier Abnova Corporation Supplier No. MAB6227

Description

Mouse monoclonal antibody raised against native SELE.

The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq

Specifications

• Antigen: SELE
• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Inhibition Assays, Western Blot
• Classification: Monoclonal
• Clone: 1.2B6
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against native SELE.
• Dilution: Flow Cytometry (1 ug/10⁶ cells) The optimal working dilution should be determined by the end user.
• Formulation: In 100mM BBS, pH 8.2
• Gene: SELE
• Gene Alias: CD62E/ELAM/ELAM1/ESEL/LECAM2
• Gene Symbols: SELE
• Host Species: Mouse
• Immunogen: Native purified from TNF activated human umbilical vein endothelial cells .
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6401
• Test Specificity: human CD62E/E-selectin.
• Target Species: Human
• Content And Storage: Store at 4°C.
• Form: Liquid
• Isotype: IgG1