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SELP, Mouse, Clone: WGA-1, Abnova™

Catalog No. 89113454 Shop All Abnova Corporation Products
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Catalog No. Quantity
89-113-454 100 μg
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Catalog No. 89-113-454 Supplier Abnova Corporation Supplier No. MAB8380
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Description

Mouse monoclonal antibody raised against native SELP.

This gene encodes a 140kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. [provided by RefSeq

Specifications

Antigen SELP
Applications ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Western Blot
Classification Monoclonal
Clone WGA-1
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against native SELP.
Dilution ELISA (1-10 ug/mL) Flow Cytometry (1-10 ug/mL) Western Blot (5-10 ug/mL) Immunohistochemistry (Frozen sections) (5-10 ug/mL) The optimal working dilution should be determined by the end user.
Formulation Lyophilized from 10mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
Gene SELP
Gene Alias CD62/CD62P/FLJ45155/GMP140/GRMP/LECAM3/PADGEM/PSEL
Gene Symbols SELP
Host Species Mouse
Immunogen Native purified SELP from human platelets.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6403
Test Specificity This antibody reacts with GMP-140 (Pselectin) on activated human platelets; it does not react with resting platelets. It does not interfere with platelet aggregation or platelet adhesion. It does not cross-react with rabbit, rat, porcine, or canine activated platelets.
Target Species Human
Content And Storage Store at 4°C on dry atmosphere. After reconstitution with deionized waterstore at -20°C. Aliquot to avoid repeated freezing and thawing.
Form Lyophilized
Isotype IgG1
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