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SELP, Mouse, PE, Clone: AK4, Abnova™

Catalog No. 89108446 Shop All Abnova Corporation Products
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100 Reactions
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89-108-446 100 Reactions
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Catalog No. 89-108-446 Supplier Abnova Corporation Supplier No. MAB10241
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Description

Mouse monoclonal antibody raised against of SELP.

This gene encodes a 140kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. [provided by RefSeq

Specifications

Antigen SELP
Applications Flow Cytometry, Functional Assay, Immunocytochemistry, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone AK4
Conjugate PE
Description Mouse monoclonal antibody raised against of SELP.
Dilution Flow Cytometry (20 uL reagent/100 uL of whole blood or 106 cells) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.2% BSA, 0.09% sodium azide)
Gene SELP
Gene Alias CD62/CD62P/FLJ45155/GMP140/GRMP/LECAM3/PADGEM/PSEL
Gene Symbols SELP
Host Species Mouse
Immunogen Human platelets.
Purification Method Size-exclusion chromatography purification
Quantity 100 Reactions
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6403
Test Specificity SELP, a single chain type I transmembrane glycoprotein present in secretory alpha-granules in platelets, in Weibel-Palade bodies in endothelial cells and in megakaryocytes; it is relocated to the plasma membrane upon activation.
Target Species Human, Non-human Primate
Content And Storage Store at 4°C. Do not freeze.
Form Liquid
Isotype IgG1
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