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Description
This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Specifications
Specifications
| Antigen | SERPINE1 |
| Applications | ELISA |
| Classification | Monoclonal |
| Clone | 3E529 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against recombinant SERPINE1. |
| Dilution | The optimal working dilution should be determined by the end user. |
| Formulation | In 50mM sodium phosphate buffer, 100mM NaCl, 1mM EDTA, pH 6.6 |
| Gene | SERPINE1 |
| Gene Alias | PAI/PAI-1/PAI1/PLANH1 |
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