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MilliporeSigma™ Mouse anti-SKP1, Clone: 3F3.1,

Catalog No. MABS1229 Shop All MilliporeSigma Products
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MABS1229 100 μg
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Description

Mouse Monoclonal Antibody

Specifically detects SKP1 clone: 3F3.1 in Human, Mouse samples, and it is validated for Immunocytochemistry, Western Blotting

S-phase kinase-associated protein 1 (UniProt P63208; also known as Cyclin-A/CDK2-associated protein p19, OCP-2, OCP-II, Organ of Corti protein 2, Organ of Corti protein II, p19A, p19skp1, RNA polymerase II elongation factor-like protein, SIII, Transcription elongation factor B polypeptide 1-like) is encoded by the SKP1 (also known as EMC19, OCP2, SKP1A, TCEB1L) gene (Gene ID 6500) in human. Polyubiquitination of proteins is mediated by ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin ligases (E3s). There exist RING finger-type, HECT-type, and U-box type of E3 ligases. Skp1 is one of the three core components of the SCF complex (Skp1, Cullin, F-box) and functions as an adapter that bridges the F-box protein and Cullin (CUL1). SCF complex depends on various F-box proteins for specific recognition and recruitment of substrates. SCF ligase plays an important role in regulating the transitions between G1/S and G2/M phases.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SKP1
Applications Immunocytochemistry, Western Blot
Classification Monoclonal
Clone 3F3.1
Formulation Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No. P63208
Gene Symbols SKP1; EMC19; OCP2; SKP1A; TCEB1L
Host Species Mouse
Immunogen GST-tagged recombinant human SKP1 internal fragment.
Purification Method Protein G Purified
Quantity 100 μg
Regulatory Status RUO
Research Discipline Signaling
Primary or Secondary Primary
Gene ID (Entrez) NP_008861
Target Species Human, Mouse
Content And Storage Stable for one year at 2°C to 8°C from date of receipt.
Form Purified
Isotype IgG2a κ
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For Research Use Only

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