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Description
Glutamate and aspartate are excitatory neurotransmitters that have been implicated in a number of pathologic states of the nervous system. Accumulation of extracellular excitatory amino acids can be cytotoxic and may also lower the seizure threshold in epilepsy. EAAT1 (SLC1A3) is a member of a family of high-affinity sodium-dependent transporter molecules that regulate neurotransmitter concentrations at the excitatory glutamatergic synapses of the mammalian central nervous system (Kirschner et al., 1994 [PubMed 8001975]).[supplied by OMIM
Specifications
Specifications
| Antigen | SLC1A3 |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Clone | 3D1 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a partial recombinant SLC1A3. |
| Formulation | ascites with no preservative |
| Gene | SLC1A3 |
| Gene Accession No. | NM_004172 |
| Gene Alias | EA6/EAAT1/FLJ25094/GLAST/GLAST1 |
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