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SNCA, Mouse, Clone: 2A7, Abnova™

Catalog No. 89112240 Shop All Abnova Corporation Products
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89-112-240 100 μL
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Catalog No. 89-112-240 Supplier Abnova Corporation Supplier No. MAB5383
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Mouse monoclonal antibody raised against recombinant SNCA.

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq]

Specifications

Antigen SNCA
Applications ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Classification Monoclonal
Clone 2A7
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against recombinant SNCA.
Dilution Western Blot (1:10000) Immunofluorescence (1:1000) The optimal working dilution should be determined by the end user.
Formulation In ascites (5mM sodium azide)
Gene SNCA
Gene Alias MGC110988/NACP/PARK1/PARK4/PD1
Gene Symbols SNCA
Host Species Mouse
Immunogen Recombinant His fusion protein corresponding to human SNCA.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6622
Target Species Human, Mammalia
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG1
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