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Description
This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq
Specifications
Specifications
| Antigen | SOS1 |
| Applications | Immunocytochemistry, Immunofluorescence, Western Blot |
| Classification | Monoclonal |
| Clone | SOS-01 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against synthetic peptide of SOS1. |
| Dilution | Western Blot (1 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS, pH 7.4 (0.09% sodium azide) |
| Gene | SOS1 |
| Gene Alias | GF1/GGF1/GINGF/HGF/NS4 |
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