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SPANXB1, Mouse, Clone: 2E12, Abnova™

Mouse monoclonal antibody raised against a full-length recombinant SPANXB1.

Manufacturer:  Abnova Corporation H00728695M04A

Catalog No. 89-107-811


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Description

Description

Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene maps to chromosome X in a head-to-tail orientation with SPANX family member B2, which appears to be a duplication of the B1 locus. The SPANXB genes are unique members of this gene family, since they contain an additional 18 nt in their coding region compared to the majority of family members. Although the protein encoded by this gene contains consensus nuclear localization signals, the major site for subcellular localization of expressed protein is in the cytoplasmic droplets of ejaculated spermatozoa. This protein provides a biochemical marker for studying the unique structures in spermatazoa, while attempting to further define its role in spermatogenesis. [provided by RefSeq

Sequence: MGQQSSVRRLKRSVPCESNEANEANEANKTMPETPTGDSDPQPAPKKMKTSESSTILVVRYRRNVKRTSPEELVNDHARENRINPDQMEEEEFIEITTERPKK
Specifications

Specifications

SPANXB1
Monoclonal
Unconjugated
ascites with no preservative
BC034472
B1/SPANX-B/SPANXB
Mouse
IgM Kappa
RUO
Antibody
Monoclonal
Human
ELISA, Western Blot
2E12
Mouse monoclonal antibody raised against a full-length recombinant SPANXB1.
SPANXB1
Ascites
SPANXB1
SPANXB1 (AAH34472,1 a.a. ∽ 103 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
200 uL
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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