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SSX4 (M02A), Mouse anti-Human, Clone: 3E10, Abnova™

Catalog No. 89105509 Shop All Abnova Corporation Products
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89-105-509 200 μL
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Catalog No. 89-105-509 Supplier Abnova Corporation Supplier No. H00006759M02A
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Description

Mouse monoclonal antibody raised against a partial recombinant SSX4.

The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4, represents the more telomeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq

Sequence: RNQVERPQMTFGSLQRIFPKIMPKKPAEEENGLKEVPEASGPQNDGKQLCPPGNPSTLEKINKTSGPKRGKHAWTHRLRERKQLVVYEEISDPEEDDE

Specifications

Antigen SSX4
Applications ELISA, Western Blot
Classification Monoclonal
Clone 3E10
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against a partial recombinant SSX4.
Formulation ascites with no preservative
Gene SSX4
Gene Accession No. NM_005636
Gene Alias MGC119056/MGC12411
Gene Symbols SSX4
Host Species Mouse
Immunogen SSX4 (NP_005627,91 a.a. ∽ 188 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6759
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Product Type Antibody
Form Ascites
Isotype IgG2a κ
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