STAT1, Mouse, Clone: SM2, Abnova™

Catalog No.	Quantity
89-108-290	100 μg

Catalog No. 89-108-290 Supplier Abnova Corporation Supplier No. MAB0962

Description

Mouse monoclonal antibody raised against synthetic peptide of STAT1.

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq

Specifications

• Antigen: STAT1
• Applications: Immunoprecipitation, Western Blot
• Classification: Monoclonal
• Clone: SM2
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against synthetic peptide of STAT1.
• Dilution: The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.4 (0.09% sodium azide)
• Gene: STAT1
• Gene Alias: DKFZp686B04100/ISGF-3/STAT91
• Gene Symbols: STAT1
• Host Species: Mouse
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to amino acids 8-23 of human STAT1.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6772
• Test Specificity: This antibody recognizes an epitope included within amino acids 8-23 of STAT1, a 91 KDa transcriptional factor involved in a variety of systems including antiviral responses and interferon alpha (IFN-alpha) and gamma (IFN-gamma) signal transduction.
• Target Species: Human
• Content And Storage: Store at 4°C. Do not freeze.
  Avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1