STAT5B, Mouse, Clone: A2H6, Abnova™

Catalog No.	Quantity
89-112-865	500 μg

Catalog No. 89-112-865 Supplier Abnova Corporation Supplier No. MAB6427

Description

Mouse monoclonal antibody raised against synthetic phosphopeptide of STAT5B.

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq

Specifications

• Antigen: STAT5B
• Applications: ELISA
• Classification: Monoclonal
• Clone: A2H6
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against synthetic phosphopeptide of STAT5B.
• Dilution: ELISA (1 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: Lyophilized from 10mM PBS, pH 7.0
• Gene: STAT5B
• Gene Alias: STAT5
• Gene Symbols: STAT5B
• Host Species: Mouse
• Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T694 of human STAT5B.
• Quantity: 500 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6777
• Test Specificity: Reactive to the immunogen and peptide-BSA conjugating.
• Target Species: Human
• Content And Storage: Store at -20°C on dry atmosphere. After reconstitution with deionized water store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Form: Lyophilized
• Isotype: IgG2b κ