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Description
Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF1, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM
Specifications
Specifications
| Antigen | SULF1 |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Clone | 1A4 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a partial recombinant SULF1. |
| Formulation | ascites with no preservative |
| Gene | SULF1 |
| Gene Accession No. | NM_015170 |
| Gene Alias | FLJ30905/FLJ38022/FLJ41750/HSULF-1/KIAA1077/SULF-1 |
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