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Description
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
Specifications
Specifications
| Antigen | TBX5 |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Clone | 7B11 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against recombinant TBX5. |
| Dilution | ELISA (1:10000) Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user. |
| Formulation | In ascites (0.03% sodium azide) |
| Gene | TBX5 |
| Gene Alias | HOS |
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