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TCEB2, Mouse, Clone: 9y74, Abnova™

Catalog No. 89113584 Shop All Abnova Corporation Products
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89-113-584 100 μL
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Catalog No. 89-113-584 Supplier Abnova Corporation Supplier No. MAB8790
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Mouse monoclonal antibody raised against full-length recombinant TCEB2.

This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Pseudogenes have been identified on chromosomes 11 and 13. [provided by RefSeq

Specifications

Antigen TCEB2
Applications ELISA, Western Blot
Classification Monoclonal
Clone 9y74
Concentration 1 ug/uL
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against full length recombinant TCEB2.
Dilution Western Blot (1:1000) The optimal working dilution should be determined by the end user.
Formulation In citrate-Tris-HCl, pH 7.0 (0.02% Proclin 300)
Gene TCEB2
Gene Alias ELOB/SIII
Gene Symbols TCEB2
Host Species Mouse
Immunogen Recombinant protein corresponding to full length human TCEB2.
Purification Method Affinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6923
Test Specificity This antibody recognizes recombinant protein TCEB2.
Target Species Human
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG1
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