TDP1, Mouse, Clone: AT1F2, Abnova™

Catalog No.	Quantity
89-112-918	100 μL

Catalog No. 89-112-918 Supplier Abnova Corporation Supplier No. MAB6511

Description

Mouse monoclonal antibody raised aganist full-length recombinant TDP1.

The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform. [provided by RefSeq

Specifications

• Antigen: TDP1
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: AT1F2
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised aganist full length recombinant TDP1.
• Dilution: The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.4 (0.09% sodium azide)
• Gene: TDP1
• Gene Alias: FLJ11090/MGC104252
• Gene Symbols: TDP1
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to full length human TDP1.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 55775
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG2b κ