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Description
The tectorial membrane is an extracellular matrix of the inner ear that contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia, and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals. Alpha-tectorin is one of the major noncollagenous components of the tectorial membrane. Mutations in the TECTA gene have been shown to be responsible for autosomal dominant nonsyndromic hearing impairment and a recessive form of sensorineural pre-lingual nonsyndromic deafness. [provided by RefSeq
Specifications
Specifications
| Antigen | TECTA |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Mouse polyclonal antibody raised against a partial recombinant TECTA. |
| Formulation | 50% glycerol |
| Gene | TECTA |
| Gene Accession No. | NM_005422 |
| Gene Alias | DFNA12/DFNA8/DFNB21 |
| Gene Symbols | TECTA |
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