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Terminal Transferase (TdT) Mouse anti-Human, Brilliant Violet 421, Clone: E17-1519, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 565230

Catalog No. BDB565230


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Description

Description

The E17-1519 monoclonal antibody specifically recognizes Terminal deoxynucleotidyl transferase (TdT), which is also known as Terminal transferase, or DNA nucleotidylexotransferase (DNTT). TdT is a 60 kDa nuclear polymerase that catalyzes the template-independent addition of deoxynucleotides to the 3'-hydroxyl termini of single-stranded oligonucleotide primer segments. TdT can contribute to antigen receptor diversity by N region diversification of rearranging immunoglobulin heavy chain and T cell receptor gene segments during pre-B and pre-T cell development. It is also expressed by certain lymphomas and leukemias.

The antibody was conjugated to BD Horizon BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50-nm filter). BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates.

Specifications

Specifications

Terminal Transferase (TdT)
E17-1519
TdT; DNTT; Terminal transferase; Terminal addition enzyme
Affinity Purified
Purified Human TdT
Affinity Chromatography
RUO
Primary
Human
Flow Cytometry, Immunocytochemistry
Brilliant Violet 421
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Murine
IgG1, κ
100 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
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