TGFB1, Mouse, Clone: 2C6, Abnova™

Catalog No.	Quantity
89-112-821	500 μg

Catalog No. 89-112-821 Supplier Abnova Corporation Supplier No. MAB6319

Description

Mouse monoclonal antibody raised against native TGFB1.

TGFB is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. TGFB acts synergistically with TGFA (MIM 190170) in inducing transformation. It also acts as a negative autocrine growth factor. Dysregulation of TGFB activation and signaling may result in apoptosis. Many cells synthesize TGFB and almost all of them have specific receptors for this peptide. TGFB1, TGFB2 (MIM 190220), and TGFB3 (MIM 190230) all function through the same receptor signaling systems.[supplied by OMIM

Specifications

• Antigen: TGFB1
• Applications: ELISA, Immunohistochemistry, Inhibition Assays, Western Blot
• Classification: Monoclonal
• Clone: 2C6
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against native TGFB1.
• Dilution: Western Blot (50-500 ng/mL) The optimal working dilution should be determined by the end user.
• Formulation: Lyophilized from 10mM PBS, pH 7.0
• Gene: TGFB1
• Gene Alias: CED/DPD1/TGFB/TGFbeta
• Gene Symbols: TGFB1
• Host Species: Mouse
• Immunogen: Native purified human platelets TGFB1.
• Quantity: 500 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7040
• Test Specificity: This antibody reacts with the dimeric (25 KDa) and monomeric (12.5 KDa) forms of TGFB1 under both non-reducing and reducing conditions respectively.
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot after reconstitution to avoid repeated freezing and thawing.
• Form: Lyophilized
• Isotype: IgG1 κ