THRB, Mouse, Clone: 2386, Abnova™

Catalog No.	Quantity
89-110-626	100 μL

Catalog No. 89-110-626 Supplier Abnova Corporation Supplier No. MAB1784

Description

Mouse monoclonal antibody raised against synthetic peptide of THRB.

The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq

Specifications

• Antigen: THRB
• Applications: Western Blot
• Classification: Monoclonal
• Clone: 2386
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against synthetic peptide of THRB.
• Dilution: Western Blot (1:1000) The optimal working dilution should be determined by the end user.
• Formulation: In 10mM HEPES, 150mM NaCl, pH 7.5 (50% glycerol, 10% BSA)
• Gene: THRB
• Gene Alias: ERBA-BETA/ERBA2/GRTH/MGC126109/MGC126110/NR1A2/PRTH/THR1/THRB1/THRB2
• Gene Symbols: THRB
• Host Species: Mouse
• Immunogen: A synthetic peptide corresponding to N-terminus human THRB.
• Purification Method: Protein G purification
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7068
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1