TLR5, Mouse, Clone: 19D759.2, Abnova™

Catalog No.	Quantity
89-107-876	100 μg

Catalog No. 89-107-876 Supplier Abnova Corporation Supplier No. MAB0109

Description

Mouse monoclonal antibody raised against synthetic peptide of TLR5.

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene product is expressed in myelomonocytic cells, and recognizes bacterial flagellin, a principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB and stimulates tumour necrosis factor-alpha production. [provided by RefSeq

Specifications

• Antigen: TLR5
• Applications: Flow Cytometry, Immunohistochemistry, Western Blot
• Classification: Monoclonal
• Clone: 19D759.2
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against synthetic peptide of TLR5.
• Dilution: The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.05% BSA, 0.05% sodium azide)
• Gene: TLR5
• Gene Alias: FLJ10052/MGC126430/MGC126431/SLEB1/TIL3
• Gene Symbols: TLR5
• Host Species: Mouse
• Immunogen: A synthetic peptide corresponding to amino acids 700-800 of human TLR5.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7100
• Target Species: Human, Mouse
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG2a