TLR5, Mouse, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-105-626	50 μL

Catalog No. 89-105-626 Supplier Abnova Corporation Supplier No. H00007100A01

Description

Mouse polyclonal antibody raised against a partial recombinant TLR5.

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene product is expressed in myelomonocytic cells, and recognizes bacterial flagellin, a principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB and stimulates tumour necrosis factor-alpha production. [provided by RefSeq

Sequence: LPPGVFSHLTALRGLSLNSNRLTVLSHNDLPANLEILDISRNQLLAPNPDVFVSLSVLDITHNKFICECELSTFINWLNHTNVTIAGPPADIYCVYPDSFSGVSLFSLSTEGCDEEEV

Specifications

• Antigen: TLR5
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Mouse polyclonal antibody raised against a partial recombinant TLR5.
• Formulation: 50% glycerol
• Gene: TLR5
• Gene Accession No.: NM_003268
• Gene Alias: FLJ10052/MGC126430/MGC126431/SLEB1/TIL3
• Gene Symbols: TLR5
• Host Species: Mouse
• Immunogen: TLR5 (NP_003259, 517 a.a. ∽ 634 a.a) partial recombinant protein with GST tag.
• Quantity: 50 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7100
• Target Species: Human
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Form: Antisera

For Research Use Only