TLR7, Mouse, Clone: 4F4, Abnova™

Catalog No.	Quantity
89-108-814	100 μL

Catalog No. 89-108-814 Supplier Abnova Corporation Supplier No. MAB1062

Description

Mouse monoclonal antibody raised against partial recombinant TLR7.

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X. [provided by RefSeq

Specifications

• Antigen: TLR7
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: 4F4
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against partial recombinant TLR7.
• Dilution: Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.4 (0.09% sodium azide)
• Gene: TLR7
• Gene Accession No.: NM_016562
• Gene Symbols: TLR7
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to amino acids 451-500 of human TLR7.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 51284
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1 κ