TLR9 isoform A, Mouse, Clone: 26C593.2, Abnova™

Catalog No.	Quantity
89-107-858	100 μg

Catalog No. 89-107-858 Supplier Abnova Corporation Supplier No. MAB0087

Description

Mouse monoclonal antibody raised against synthetic peptide of TLR9.

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. [provided by RefSeq

Specifications

• Antigen: TLR9 isoform A
• Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen), Western Blot
• Classification: Monoclonal
• Clone: 26C593.2
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against synthetic peptide of TLR9.
• Dilution: ELISA (1:100-1:2000) Flow Cytometry Immunocytochemistry (1:10-1:500) Immunofluorescence (1:10-1:500) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL) Immunoprecipitation (1:10-1:500) Western Blot (2-5 ug/mL)
• Formulation: In PBS (0.05% BSA, 0.05% sodium azide)
• Gene: TLR9
• Gene Alias: CD289
• Gene Symbols: TLR9
• Host Species: Mouse
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to amino acids 268-300 of human TLR9 isoform A.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 54106
• Target Species: Human, Monkey, Mouse, Rat
• Content And Storage: Store at 4°C for short term. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1 κ