TNF, Mouse, Clone: 4E1, Abnova™

Catalog No.	Quantity
89-113-896	100 μg

Catalog No. 89-113-896 Supplier Abnova Corporation Supplier No. MAB9938

Description

Mouse monoclonal antibody raised against full-length recombinant TNF.

This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq

Specifications

• Antigen: TNF
• Applications: ELISA, Immunohistochemistry, Western Blot
• Classification: Monoclonal
• Clone: 4E1
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against full length recombinant TNF.
• Dilution: Western blot (1:1000) Immunohistochemistry (1:10) The optimal working dilution should be determined by the end user.
• Formulation: In Citrate-Tris-HCl buffer, pH 7.0 (0.02% Proclin 300)
• Gene: TNF
• Gene Accession No.: NM_000594.2
• Gene Alias: DIF/TNF-alpha/TNFA/TNFSF2
• Gene Symbols: TNF
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to full length human TNF.
• Purification Method: Affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7124
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1