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TNFRSF10B, Mouse, FITC, Clone: DR5-01-1, Abnova™

Catalog No. 89111859 Shop All Abnova Corporation Products
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89-111-859 100 μg
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Catalog No. 89-111-859 Supplier Abnova Corporation Supplier No. MAB4505
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Description

Mouse monoclonal antibody raised against partial recombinant TNFRSF10B.

The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one noncoding transcript have been found for this gene. [provided by RefSeq

Specifications

Antigen TNFRSF10B
Applications Flow Cytometry
Classification Monoclonal
Clone DR5-01-1
Concentration 0.1 mg/mL
Conjugate FITC
Description Mouse monoclonal antibody raised against partial recombinant TNFRSF10B.
Dilution Flow Cytometry (5 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.2% BSA, 0.09% sodium azide)
Gene TNFRSF10B
Gene Alias CD262/DR5/KILLER/KILLER/DR5/TRAIL-R2/TRAILR2/TRICK2/TRICK2A/TRICK2B/TRICKB/ZTNFR9
Gene Symbols TNFRSF10B
Host Species Mouse
Immunogen Recombinant Fc fusion protein corresponding to partial human TNFRSF10B.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8795
Test Specificity This antibody recognizes an extracellular domain of TRAIL-R2 (DR5). TRAIL-R2 is one of two TNF superfamily member intracellular death domain containing receptors for TRAIL (APO2L).
Target Species Human
Content And Storage Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG1
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