TNFRSF10C, Mouse, PE, Clone: TRAIL-R3-02, Abnova™

Catalog No.	Quantity
89-112-142	100 μg

Catalog No. 89-112-142 Supplier Abnova Corporation Supplier No. MAB5138

Description

Mouse monoclonal antibody raised against recombinant TNFRSF10C.

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq

Specifications

• Antigen: TNFRSF10C
• Applications: Flow Cytometry
• Classification: Monoclonal
• Clone: TRAIL-R3-02
• Concentration: 0.1 mg/mL
• Conjugate: PE
• Description: Mouse monoclonal antibody raised against recombinant TNFRSF10C.
• Dilution: Flow Cytometry (3 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.2% BSA, 0.09% sodium azide)
• Gene: TNFRSF10C
• Gene Alias: CD263/DCR1/LIT/MGC149501/MGC149502/TRAILR3/TRID
• Gene Symbols: TNFRSF10C
• Host Species: Mouse
• Immunogen: Recombinant Fc fusion protein corresponding to amino acids 1-280 of TNFRSF10C.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 8794
• Test Specificity: This antibody reacts with TRAIL-R3, a 35 KDa GPI-anchored extracellular membrane protein expressed mainly on neutrophils.
• Target Species: Human
• Content And Storage: Store in the dark at 4°C. Do not freeze.
  Avoid prolonged exposure to light.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1