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Description
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq]
Specifications
Specifications
| Antigen | TNFRSF18 |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Mouse polyclonal antibody raised against a partial recombinant TNFRSF18. |
| Formulation | 50% glycerol |
| Gene | TNFRSF18 |
| Gene Accession No. | NM_004195 |
| Gene Alias | AITR/GITR/GITR-D |
| Gene Symbols | TNFRSF18 |
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