TNFRSF21, Mouse, Clone: DR-6-04-EC, Abnova™

Mouse monoclonal antibody raised against partial recombinant TNFRSF21.

Supplier:  Abnova Corporation MAB3877

Catalog No. 89-111-645

Description

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors. Knockout studies in mice suggested that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. [provided by RefSeq

Specifications

• Antigen: TNFRSF21
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Flow Cytometry (1 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: TNFRSF21
• Gene Symbols: TNFRSF21
• Immunogen: Recombinant Fc fusion protein corresponding to amino acids 42-335 extracellular region of human TNFRSF21.
• Regulatory Status: RUO
• Gene ID (Entrez): 27242
• Target Species: Human
• Form: Liquid

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation
• Clone: DR-6-04-EC
• Description: Mouse monoclonal antibody raised against partial recombinant TNFRSF21.
• Formulation: In PBS, pH 7.4 (0.09% sodium azide)
• Gene Alias: BM-018/DR6/MGC31965
• Host Species: Mouse
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody recognizes human DR6 (Death receptor-6), a type I transmembrane protein containing cytoplasmic death domain, widely expressed in most human tissues and cell lines.
• Content And Storage: Store at 4°C. Do not freeze.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1