TNFRSF8, Mouse, APC, Clone: MEM-268, Abnova™

Catalog No.	Quantity
89-112-112	100 Reactions

Catalog No. 89-112-112 Supplier Abnova Corporation Supplier No. MAB5098

Description

Mouse monoclonal antibody raised against TNFRSF8.

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq

Specifications

• Antigen: TNFRSF8
• Applications: Flow Cytometry
• Classification: Monoclonal
• Clone: MEM-268
• Conjugate: APC
• Description: Mouse monoclonal antibody raised against TNFRSF8.
• Dilution: Flow Cytometry (10 ul in human blood cells 100 ul in whole blood or 10⁶ cells in a suspension) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.2% BSA, 0.09% sodium azide)
• Gene: TNFRSF8
• Gene Alias: CD30/D1S166E/KI-1
• Gene Symbols: TNFRSF8
• Host Species: Mouse
• Immunogen: Expression vector containing CD30 cDNA (booster suspension of THP-1 cell line).
• Quantity: 100 Reactions
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 943
• Test Specificity: This antibody recognizes extracellular part of CD30 (Ki-1 antigen), a 105 KDa single chain glycoprotein expressed on Hodgkin's and Reed-Sternberg cells.
• Target Species: Human
• Content And Storage: Store in the dark at 4°C. Do not freeze.
  Avoid prolonged exposure to light.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG