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TNFSF10, Mouse, Clone: SB91a1, Abnova™

Catalog No. 89113385 Shop All Abnova Corporation Products
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500 μg
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89-113-385 500 μg
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Catalog No. 89-113-385 Supplier Abnova Corporation Supplier No. MAB8218
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Description

Mouse monoclonal antibody raised against full-length recombinant TNFSF10.

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. [provided by RefSeq

Specifications

Antigen TNFSF10
Applications ELISA
Classification Monoclonal
Clone SB91a
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against full length recombinant TNFSF10.
Dilution ELISA (0.1-1.0 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In 100mM BBS, pH 8.0
Gene TNFSF10
Gene Alias APO2L/Apo-2L/CD253/TL2/TRAIL
Gene Symbols TNFSF10
Host Species Mouse
Immunogen Recombinant protein corresponding to full length human CASP3.
Quantity 500 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8743
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
Isotype IgG2b
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