TNNI3, Mouse, Clone: 3A10A12, 5C3A7, Abnova™

Catalog No.	Quantity
89-113-423	100 μL

Catalog No. 89-113-423 Supplier Abnova Corporation Supplier No. MAB8299

Description

Mouse monoclonal antibody raised against partial recombinant TNNI3.

Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq

Specifications

• Antigen: TNNI3
• Applications: ELISA, Immunohistochemistry, Immunohistochemistry (Frozen), Western Blot
• Classification: Monoclonal
• Clone: 3A10A12, 5C3A7
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against partial recombinant TNNI3.
• Dilution: Western Blot (1:200-1:1000) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100-1:1000) Immunohistochemistry (Frozen sections) (1:200-1:1000) ELISA (1:10000) The optimal working dilution should be determined by the end
• Formulation: In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide)
• Gene: TNNI3
• Gene Alias: CMD2A/CMH7/MGC116817/RCM1/TNNC1/cTnI
• Gene Symbols: TNNI3
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to truncated human TNNI3.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7137
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid