TNNI3, Mouse, Clone: P420, Abnova™

Catalog No.	Quantity
89-111-982	1 mg

Catalog No. 89-111-982 Supplier Abnova Corporation Supplier No. MAB4761

Description

Mouse monoclonal antibody raised against native TNNI3.

Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq

Specifications

• Antigen: TNNI3
• Applications: ELISA, Sandwich ELISA
• Classification: Monoclonal
• Clone: P420
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against native TNNI3.
• Dilution: The optimal working dilution should be determined by the end user.
• Formulation: In 10mM sodium phosphate buffer, 0.85% NaCl, pH 7.2 (0.05% sodium azide)
• Gene: TNNI3
• Gene Alias: CMD2A/CMH7/MGC116817/RCM1/TNNC1/cTnI
• Gene Symbols: TNNI3
• Host Species: Mouse
• Immunogen: Native purified human TNNI3.
• Quantity: 1 mg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7137
• Test Specificity: Reacts with human cardiac Troponin I. Cross reactivity with human skeletal TNI is <0.1% as measured by ELISA.
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1 κ