TNNI3, Mouse, Clone: TPC-110, Abnova™

Mouse monoclonal antibody raised against native human TNNI3.

Supplier:  Abnova Corporation MAB1417

Catalog No. 89-110-423

Description

Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq

Specifications

• Antigen: TNNI3
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Sandwich ELISA The optimal working dilution should be determined by the end user.
• Gene: TNNI3
• Gene Symbols: TNNI3
• Immunogen: Native purified human TNNI3.
• Regulatory Status: RUO
• Gene ID (Entrez): 7137
• Content And Storage: Store at 4°C.
• Isotype: IgG1

• Applications: ELISA
• Clone: TPC-110
• Description: Mouse monoclonal antibody raised against native human TNNI3.
• Formulation: In 15mM KPO₄ buffer, 0.85% NaCl, pH 7.4 (0.09% sodium azide)
• Gene Alias: CMD2A/CMH7/MGC116817/RCM1/TNNC1/cTnI
• Host Species: Mouse
• Quantity: 1 mg
• Primary or Secondary: Primary
• Test Specificity: This antibody is specific to TNNI3. Not reactive to human skeletal muscle Troponin I, human skeletal Troponin T, human cardiac Troponin T, or human Troponin C.
• Form: Liquid