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TPO, Mouse, Clone: AC25, Abnova™

Catalog No. 89113683 Shop All Abnova Corporation Products
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89-113-683 3 x 1 mL
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Catalog No. 89-113-683 Supplier Abnova Corporation Supplier No. MAB9546

Description

Mouse monoclonal antibody raised against partial recombinant TPO.

This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Additional splice variants have been described but their biological natures have not been determined. [provided by RefSeq

Specifications

Antigen TPO
Applications Immunohistochemistry
Classification Monoclonal
Clone AC25
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against partial recombinant TPO.
Dilution Immunohistochemistry (1:80) The optimal working dilution should be determined by the end user.
Formulation In tissue culture supernatant (0.09% sodium azide)
Gene TPO
Gene Alias MSA/TPX
Gene Symbols TPO
Host Species Mouse
Immunogen Recombinant protein corresponding to 105 amino acids near N-terminus of human TPO.
Quantity 3 x 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7173
Target Species Human
Content And Storage Store at 4°C. Do not freeze.
Form Liquid
Isotype IgG1
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