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Mouse anti-Transglutaminase 2/TGM2, Clone: SPM592, Novus Biologicals™

Mouse Monoclonal Antibody

$129.00 - $299.00

Specifications

Antigen Transglutaminase 2/TGM2
Clone SPM592
Concentration 0.2mg/mL
Immunogen Recombinant full-length human TGM2 protein
Gene ID (Entrez) 7052
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Products 3
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
NBP24459500 View Documents Novus BiologicalsSupplier Diversity Partner
NBP2445950.02MG
0.02 mg Each for $129.00
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NBP24459501 View Documents Novus BiologicalsSupplier Diversity Partner
NBP2445950.1MG
0.1 mg Each for $299.00
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NBP24459502 View Documents Novus BiologicalsSupplier Diversity Partner
NBP2445950.2MG
0.2 mg This item has been discontinued and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
Description

Description

Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Transglutaminase 2/TGM2 Monoclonal antibody specifically detects Transglutaminase 2/TGM2 in Human, Mouse, Rat, Monkey, Rabbit samples. It is validated for Flow Cytometry, Immunohistochemistry-Paraffin, Immunofluorescence.
Specifications

Specifications

Transglutaminase 2/TGM2
0.2mg/mL
7052
Monoclonal
Mouse
IgG2a Kappa
Purified
RUO
Protein A or G purified
SPM592
Recombinant full-length human TGM2 protein
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Primary
Recognizes a 77-85kDa protein, identified as cellular or tissue transglutaminase II (TGase II). Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. The identification of transglutaminase as the main antigen of endomysium antibodies allows a new diagnostic approach to celiac disease (CD), a genetic, immunologically mediated small bowel enteropathy that causes malabsorption. TGase II is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound healing.
Unconjugated
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Store at 4C.

For Research Use Only

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