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Description
The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq
Specifications
Specifications
| Antigen | TRPC6 |
| Applications | ELISA, Immunohistochemistry, Western Blot |
| Classification | Monoclonal |
| Clone | 3F2.H10.F2 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against synthetic peptide of TRPC6 . |
| Dilution | ELISA (1:10000-1:50000) Western Blot (1:500-1:2000) Immunohistochemistry (2.5 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In 20mM KH2PO4, 150mM NaCl, pH 7.2 (0.01% sodium azide) |
| Gene | TRPC6 |
| Gene Alias | FLJ11098/FLJ14863/FSGS2/TRP6 |
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