MilliporeSigma™ Mouse anti-TRPM1, Clone: 545H5,

Mouse Monoclonal Antibody

Supplier:  MilliporeSigma™ MABN1841

Catalog No. MABN1841

Description

Specifically detects TRPM1 clone: 545H5 in Mouse samples, and it is validated for Western Blotting

Transient receptor potential cation channel subfamily M member 1 (UniProt Q2TV84; also known as Long transient receptor potential channel 1, LTrpC1, Melastatin-1) is encoded by the Trpm1 (also known as CSNB1C, Ltrpc1, Mlsn1, MLSN1) gene (Gene ID 17364) in murine species. TRPM1 belongs to the TRPM (M for melastatin) subgroup of the family of transient receptor potential (TRP) channels. TRPM1 is a ∼180kDa protein localized to the somas and dendrites of both rod and cone metabotropic (ON) bipolar cells and colocalized with mGluR6 at the dendritic tips, where it plays an important role in light-regulated conductance in ON bipolar cells. Genetic lesions in the TRPM1 gene are associated with complete congenital stationary night blindness in human and TRPM1 knock-out mice have a no-b-wave (nob) electroretinogram phenotype.

Specifications

• Antigen: TRPM1
• Classification: Monoclonal
• Formulation: Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
• Gene Symbols: Trpm1; CSNB1C; Ltrpc1; Mlsn1; MLSN1
• Immunogen: Detergent stabilized, C-terminal 1D4 tag-tagged recombinant full-length mouse TRPM1.
• Quantity: 100 μg
• Research Discipline: Neuroscience
• Gene ID (Entrez): NM_001039104.2
• Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
• Isotype: IgG2b κ

• Applications: Western Blot
• Clone: 545H5
• Gene Accession No.: Q2TV84
• Host Species: Mouse
• Purification Method: Protein G Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Mouse
• Form: Purified

For Research Use Only