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UBA7, Mouse, Clone: 5B10, Abnova™

Catalog No. 89108530 Shop All Abnova Corporation Products
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89-108-530 100 μL
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Catalog No. 89-108-530 Supplier Abnova Corporation Supplier No. MAB10343
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Mouse monoclonal antibody raised against recombinant UBA7.

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. [provided by RefSeq

Specifications

Antigen UBA7
Applications ELISA, Western Blot
Classification Monoclonal
Clone 5B10
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against recombinant UBA7.
Dilution ELISA (1:10000) Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user.
Formulation In ascites (0.03% sodium azide)
Gene UBA7
Gene Alias D8/MGC12713/UBA1B/UBE1L/UBE2
Gene Symbols UBA7
Host Species Mouse
Immunogen Recombinant protein corresponding to human UBA7.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7318
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG1
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