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UBR2, Mouse, Clone: 4G4, Abnova™

Catalog No. 89106580 Shop All Abnova Corporation Products
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200 μL
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89-106-580 200 μL
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Catalog No. 89-106-580 Supplier Abnova Corporation Supplier No. H00023304M01A
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Description

Mouse monoclonal antibody raised against a partial recombinant UBR2.

Proteolysis by the ubiquitin-proteasome system controls the concentration of many regulatory proteins. The selectivity of ubiquitylation is determined by ubiquitin E3 ligases, which recognize the substrate's destabilization signal, or degron. The E3 ligase UBR2 participates in the N-end rule pathway, which targets proteins bearing an N-terminal degron, or N-degron (Kwon et al., 2003 [PubMed 14585983]).[supplied by OMIM

Sequence: MASELEPEVQAIDRSLLECSAEEIAGKWLQATDLTREVYQHLAHYVPKIYCRGPNPFPQKEDMLAQHVLLGPMEWYLCGEDPAFGFPKLEQANKPSHLCG

Specifications

Antigen UBR2
Applications ELISA, Western Blot
Classification Monoclonal
Clone 4G4
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against a partial recombinant UBR2.
Formulation ascites with no preservative
Gene UBR2
Gene Accession No. NM_015255
Gene Alias C6orf133/DKFZp686C08114/KIAA0349/MGC71112/RP3-392M17.3/bA49A4.1/dJ242G1.1/dJ392M17.3
Gene Symbols UBR2
Host Species Mouse
Immunogen UBR2 (NP_056070,1 a.a. ∽ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23304
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Product Type Antibody
Form Ascites
Isotype IgG2a κ
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