VAMP2, Mouse, Clone: 3E5, Abnova™

Mouse monoclonal antibody raised against partial recombinant VAMP2.

Supplier:  Abnova Corporation MAB1097

Catalog No. 89-109-185

Description

The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25kDa synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25kDa, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG. [provided by RefSeq

Specifications

• Antigen: VAMP2
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Western Blot (1:2000-1:3000) The optimal working dilution should be determined by the end user.
• Gene: VAMP2
• Gene Alias: FLJ11460/SYB2/VAMP-2
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Form: Liquid

• Applications: ELISA, Western Blot
• Clone: 3E5
• Description: Mouse monoclonal antibody raised against partial recombinant VAMP2.
• Formulation: In PBS, pH 7.4 (0.09% sodium azide)
• Gene Accession No.: NM_014232
• Gene Symbols: VAMP2
• Immunogen: Recombinant protein corresponding to amino acids 1-89 of human VAMP2.
• Regulatory Status: RUO
• Gene ID (Entrez): 6844
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1 κ