VCL, Mouse, Clone: VIN-54, Abnova™

Catalog No.	Quantity
89-110-455	100 μg

Catalog No. 89-110-455 Supplier Abnova Corporation Supplier No. MAB1490

Description

Mouse monoclonal antibody raised against native VCL.

Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq

Specifications

• Antigen: VCL
• Applications: Immunohistochemistry (Frozen), Western Blot
• Classification: Monoclonal
• Clone: hVIN-1
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against native VCL.
• Dilution: Western Blot (1-2 ug/mL) Immunohistochemistry (Frozen section) (2-4 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: Lyophilized from 1.2% sodium acetate (2mg BSA, 0.01mg sodium azide)
• Gene: VCL
• Gene Alias: CMD1W/MVCL
• Gene Symbols: VCL
• Host Species: Mouse
• Immunogen: Native purified human uterus VCL.
• Purification Method: Affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7414
• Target Species: Human
• Content And Storage: Store at -20°C on dry atmosphere. After reconstitution with 1mL of 1.2% sodium acetate or neutral PBS to a concentration of 100μg/mL store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Form: Lyophilized
• Isotype: IgG1