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  6. Mouse anti-VEGF R2/KDR/Flk-1, Clone: KDR721, Azide Free, Novus Biologicals™

Mouse anti-VEGF R2/KDR/Flk-1, Clone: KDR721, Azide Free, Novus Biologicals™
SDP

Catalog No. p-5322797 Shop All R&D Systems Products
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0.2 mg
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Catalog No. Quantity
NBP23465802 0.2 mg
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Catalog No. NBP23465802 Supplier Novus Biologicals Supplier No. NBP2346580.2 MG

Description

Mouse Monoclonal Antibody

VEGF R2/KDR/Flk-1 Monoclonal antibody specifically detects VEGF R2/KDR/Flk-1 in Human samples. It is validated for Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Frozen, Functional, CyTOF-ready.

Specifications

Antigen VEGF R2/KDR/Flk-1
Applications Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Frozen)
Classification Monoclonal
Clone KDR721
Concentration 1.0 mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry 0.5-1ug/million cells, ELISA 1-5ug/ml for coating, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Frozen 0.5-1ug/ml, Functional, CyTOF-ready
Formulation 10mM PBS - BSA free with No Preservative
Gene Accession No. P35968
Gene Alias CD309, CD309 antigen, EC 2.7.10, EC 2.7.10.1, Fetal liver kinase 1, fetal liver kinase-1, FLK-1, FLK1tyrosine kinase growth factor receptor, Kinase insert domain receptor, kinase insert domain receptor (a type III receptor tyrosine kinase), Protein-tyrosine kinase receptor flk-1, soluble VEGFR2, vascular endothelial growth factor receptor 2, VEGFR, VEGFR2, VEGFR-2
Gene Symbols KDR
Host Species Mouse
Immunogen Recombinant human VEGF-R2 protein
Purification Method Protein A purified
Quantity 0.2 mg
Regulatory Status RUO
Research Discipline Angiogenesis, Cancer, Cellular Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, HIF Target Genes, Hypoxia, Phospho Specific, Signal Transduction, Stem Cell Markers, Tumor Suppressors, Tyrosine Kinases
Primary or Secondary Primary
Gene ID (Entrez) 3791
Test Specificity CD309, also known as VEGFR2, KDR3, and Flk-1 (mouse), is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Human VEGFR2 is mainly expressed by endothelial cells, embryonic tissues, and megakaryocytes. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGFR2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGFR2 with its ligands results in the receptor dimerization and auto-phosphorylation, stimulating endothelial cell proliferation and migration.
Reconstitution Protein A purified
Target Species Human
Content And Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG1 κ
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