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VEGFA, Mouse, Monoclonal Antibody, Abnova™

Catalog No. 89107917 Shop All Abnova Corporation Products
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100 μg
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89-107-917 100 μg
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Catalog No. 89-107-917 Supplier Abnova Corporation Supplier No. MAB0294
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Description

Mouse monoclonal antibody raised against full-length recombinant VEGFA.

This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms. [provided by RefSeq

Specifications

Antigen VEGFA
Applications ELISA, Immunohistochemistry, Immunohistochemistry (Frozen), Western Blot
Classification Monoclonal
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against full length recombinant VEGFA.
Dilution Western Blot (1:200 immunohistochemistry (1:50) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.2% gelatin, 0.09% sodium azide)
Gene VEGFA
Gene Alias MGC70609/VEGF/VEGF-A/VPF
Gene Symbols VEGFA
Host Species Mouse
Immunogen Recombinant protein corresponding to full length human VEGFA.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7422
Test Specificity This antibody detects the 121, 165, and 189 VEGF isoforms of human origin.
Target Species Human
Content And Storage Store at 4°C. Do not freeze.
Form Liquid
Isotype IgG1
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